Dna Repair And Recombination

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Genome Stability

Genome Stability
Author :
Publisher : Garland Science
Total Pages : 416
Release :
ISBN-10 : 9781317682318
ISBN-13 : 1317682319
Rating : 4/5 (319 Downloads)

Book Synopsis Genome Stability by : James Haber

Download or read book Genome Stability written by James Haber and published by Garland Science. This book was released on 2013-12-16 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome Stability: DNA Repair and Recombination describes the various mechanisms of repairing DNA damage by recombination, most notably the repair of chromosomal breaks. The text presents a definitive history of the evolution of molecular models of DNA repair, emphasizing current research. The book introduces the central players in recombination. An overview of the four major pathways of homologous recombinational repair is followed by a description of the several mechanisms of nonhomologous end-joining. Designed as a textbook for advanced undergraduate and graduate students with a molecular biology and genetics background, researchers and practitioners, especially in cancer biology, will also appreciate the book as a reference.


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Genomic instability is a major threat to living organisms. To counteract the damaging effects posed by endogenous and environmental agents, such as chemicals or