Inducible Lymphoid Organs

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Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity

Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity
Author :
Publisher : Frontiers Media SA
Total Pages : 237
Release :
ISBN-10 : 9782889451807
ISBN-13 : 2889451801
Rating : 4/5 (801 Downloads)

Book Synopsis Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity by : Changjun Yin

Download or read book Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity written by Changjun Yin and published by Frontiers Media SA. This book was released on 2017-05-22 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A better comprehension of these powerhouses of disease immunity will likely facilitate development to unprecedented and specific therapies to fight chronic inflammatory diseases.


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The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates w