Tumor Organoids

Download Tumor Organoids full books in PDF, epub, and Kindle. Read online free Tumor Organoids ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Tumor Organoids

Tumor Organoids
Author :
Publisher : Humana Press
Total Pages : 225
Release :
ISBN-10 : 9783319605111
ISBN-13 : 3319605119
Rating : 4/5 (119 Downloads)

Book Synopsis Tumor Organoids by : Shay Soker

Download or read book Tumor Organoids written by Shay Soker and published by Humana Press. This book was released on 2017-10-20 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer cell biology research in general, and anti-cancer drug development specifically, still relies on standard cell culture techniques that place the cells in an unnatural environment. As a consequence, growing tumor cells in plastic dishes places a selective pressure that substantially alters their original molecular and phenotypic properties.The emerging field of regenerative medicine has developed bioengineered tissue platforms that can better mimic the structure and cellular heterogeneity of in vivo tissue, and are suitable for tumor bioengineering research. Microengineering technologies have resulted in advanced methods for creating and culturing 3-D human tissue. By encapsulating the respective cell type or combining several cell types to form tissues, these model organs can be viable for longer periods of time and are cultured to develop functional properties similar to native tissues. This approach recapitulates the dynamic role of cell–cell, cell–ECM, and mechanical interactions inside the tumor. Further incorporation of cells representative of the tumor stroma, such as endothelial cells (EC) and tumor fibroblasts, can mimic the in vivo tumor microenvironment. Collectively, bioengineered tumors create an important resource for the in vitro study of tumor growth in 3D including tumor biomechanics and the effects of anti-cancer drugs on 3D tumor tissue. These technologies have the potential to overcome current limitations to genetic and histological tumor classification and development of personalized therapies.


Tumor Organoids Related Books

Tumor Organoids
Language: en
Pages: 225
Authors: Shay Soker
Categories: Medical
Type: BOOK - Published: 2017-10-20 - Publisher: Humana Press

DOWNLOAD EBOOK

Cancer cell biology research in general, and anti-cancer drug development specifically, still relies on standard cell culture techniques that place the cells in
Human Adult Stem Cells
Language: en
Pages: 218
Authors: John Masters
Categories: Medical
Type: BOOK - Published: 2009-05-30 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

The aim of volume 7 of Human Cell Culture is to provide clear and precise methods for growing primary cultures of adult stem cells from various human tissues an
Ras and Cancer in the 21st Century
Language: en
Pages: 300
Authors: Linda VanAelst
Categories: Medical
Type: BOOK - Published: 2018 - Publisher: Perspectives Cshl

DOWNLOAD EBOOK

Ras proteins are key molecular switches in cell signaling pathways that, when activated, trigger cell growth and division. Mutations that produce abnormally act
Gastrointestinal Physiology and Diseases
Language: en
Pages: 0
Authors: Andrei I. Ivanov
Categories: Science
Type: BOOK - Published: 2016-06-01 - Publisher: Humana

DOWNLOAD EBOOK

This volume provides a comprehensive collection of classical and cutting edge protocols and techniques to examine the normal development and physiological funct
Translational Regenerative Medicine
Language: en
Pages: 607
Authors: Anthony Atala
Categories: Medical
Type: BOOK - Published: 2014-12-01 - Publisher: Academic Press

DOWNLOAD EBOOK

Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regener