Applications of Nuclear Magnetic Resonance Spectroscopy to Membrane Protein Structure Determination
Author | : Sangwon Lee |
Publisher | : |
Total Pages | : 150 |
Release | : 2007 |
ISBN-10 | : 1109966512 |
ISBN-13 | : 9781109966510 |
Rating | : 4/5 (510 Downloads) |
Download or read book Applications of Nuclear Magnetic Resonance Spectroscopy to Membrane Protein Structure Determination written by Sangwon Lee and published by . This book was released on 2007 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this Thesis, methodological developments to determine membrane protein structures using solution NMR spectroscopy and results on proteins with single and multiple hydrophobic trans-membrane domains and amphipathic in-plane helices are described. Measurements of weak anisotropic interactions provide unique structural information that can complement distance information. The potential of the developed methods for high-throughput applications to structural genomics of membrane proteins is tested.