Mutant P53 And Mdm2 In Cancer

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Mutant p53 and MDM2 in Cancer
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Authors: Swati Palit Deb
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This book provides the readers with an overview of research on p53, which has been shown to play a role in numerous crucial biological pathways in normal and ca
The p53 Tumor Suppressor Pathway and Cancer
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The current year (2004) marks the Silver Anniversary of the discovery of the p53 tumor suppressor. The emerging ?eld ?rst considered p53 as a viral antigen and
Human Tumor-Derived p53 Mutants: A Growing Family of Oncoproteins
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TP53 gene mutations are present in more than half of all human cancers. The resulting proteins are mostly full-length with a single amino acid change and are ab
Mutant p53 in Cancer Progression and Personalized Therapeutic Treatments
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The P53 Protein
Language: en
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Decades of research on the tumor suppressor p53 have revealed that it plays a significant role as a "guardian of the genome," protecting cells against genotoxic