The Adenosinergic System

Download or read book The Adenosinergic System written by Micaela Morelli and published by Springer. This book was released on 2015-10-01 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adenosine A2A receptor antagonists have shown great promise in the treatment of Parkinson's Disease and alleviation of symptoms. This book addresses various aspects of this class of drugs from their chemical development to their clinical use. Among the many insightful chapters contained in this book, there are three unique reviews that have not previously been published in any format: (1) a history of istradefylline, the first A2A antagonist approved for treatment of Parkinson's Disease, (2) an overview of neuroimaging studies in human death and disease and (3) a study of urate as a possible biomarker and neuroprotectant.