The Synthesis And Structure Of Some 4 Hydroxycoumarins And Their Pharmacological Activity

Download or read book The Synthesis and Structure of Some 4-Hydroxycoumarins and Their Pharmacological Activity written by Ilia Manolov and published by Cambridge Scholars Publishing. This book was released on 2021-06-14 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coumarin is a structural fragment of different natural and synthetic compounds which demonstrate a wide range of pharmacological activities. Its derivatives are of interest in many fields because of their properties as oral anticoagulants or rodenticides, photosensitizers, anti-HIV agents and antibiotics. There has been continuous interest in the synthesis of these compounds. This book describes various experiments for modifying the structure of clinically used anticoagulants, and establishes the structure of the synthesized products through X-ray analysis. It also identifies unexpected structures in this regard, and highlights the usefulness of all these structural modifications through different biological, toxicological and pharmacological experiments.